Endocrine Abstracts

Systems biology views and studies the biological systems in the context of complex interactions between their building blocks and processes. Given its multi-level complexity, metabolic syndrome (MetS) makes a strong case for adopting the systems biology approach. Despite many MetS traits being highly heritable, it is becoming evident that the genetic contribution to these traits is mediated via gene–gene and gene– environment interactions across several spatial and t...

Metabolomics is a discipline dedicated to the global study of small molecules (i.e. metabolites), their dynamics, composition, interactions, and responses to interventions or to changes in their environment, in cells, tissues, and biofluids. Metabolites are the end products of cellular regulatory processes, and their levels can be regarded as the ultimate and amplified response of biological systems to genetic or environmental changes. However, only in the past years, technolo...